Product Information

Introducing StemOneTM

A first-in-class, standardized, off-the-shelf, allogeneic mesenchymal stem cell therapy, approved by the Drug Controller General of India (DCGI), for use in the management of Grade II and Grade III knee OA

If you need to know
about stem cells,
here’s some information.1

Stem cells are

  • Raw materials of the body from
    which all other cells are formed

  • Capable of multiplying
    by dividing into daughter cells
    and also into specialized cells
    like cartilage cells, bone cells,
    and muscle cells

Stem cells
have multiple
advantages2

  • Easy to obtain, as they
    are found in abundance

  • Can convert into several
    different cell types

  • No ethical issues,
    being readily sourced from
    various tissues

This is how
StemOneTM
works3

The stem cells in StemOneTM

  • Decrease the joint pain and
    stiffness

  • Stimulate the body’s own
    cells to repair or replace
    the cartilage tissue

  • Improve physical function

StemOneTM is prepared using cutting-edge technology4

StemOneTM is prepared using cutting-edge technology4

StemOneTM is prepared using cutting-edge technology4

1. StemOneTM is a ready to use product.
2. StemOneTM is obtained from a cell bank made by pooling of bone marrow aspirates from 3 healthy donors.
3. StemOneTM is then cryopreserved.
4. After stringent quality checks, the final StemOneTM vial is cryoshipped for delivery at -185°C to -196°C.
5.Once the StemOneTM vial is delivered, your doctor will follow a standard protocol to administer it.

You need to take certain precautions after receiving an intra-articular injection5

Do
Dont's
Do  
Dont's
0-3 Days Post IA Injection
Rest for 24 hours after the injection, except for bio breaks. Avoid strenuous or prolonged weight-bearing activities for 72 hours after the injection.
Stay hydrated, eat your regular food, and drink plenty of water to promote healing. Do not take any medications, unless specified by your doctor.
Apply only a cold pack, if required, on the injection area. Avoid massaging or applying a hot pack over the injection area.
You may take a bath with lukewarm water after 24 hours. Do not take a bath with very hot water.
Avoid smoking and drinking alcohol
3-14 Days Post IA Injection
You can gradually get back to your regular activities and exercise. Avoid consuming any alcoholic beverages in the first 7 days.
Note: Kindly contact your doctor for any further information.

StemOneTM has several merits to its credit:4

StemOneTM is prepared using cutting-edge technology4

References:

  1. Mayo Clinic Staff Stem cells: What they are and what they do. [Internet] Available from https://www.mayoclinic.org/tests-procedures/bone-marrow-transplant/in-depth/stem-cells/art-20048117 Accessed on 22 Sep 2022
  2. Loo SJQ Wong NK. Advantages and challenges of stem cell therapy for osteoarthritis (Review): Biomed Rep. 2021;15:67.
  3. Wang AT, Feng Y, Jia HH, Zhao M, Yu H. Application of mesenchymal stem cell therapy for the treatment of osteoarthritis of the knee. A concite review World Stem Cells, 2019:11(4):222-35.
  4. Data on file
  5. Northeast Knee Joint Institute Platelet Rich Plasma (Post-Procedure) Guidelines. Available from: https://nkjinstitute.com/wp-content/uploads/2019/03/PRP-Post-Procedure-Guidelines.pdf Accessed on 19 Sep 2022.

Copyright 2023 @ all Rights Reserved